Description

1-Pyrrolidinecarboxylicacid,2-Cyano-5-Formyl-,Methylester,(2R-Cis)-(9Ci) is a high-purity, chiral pyrrolidine derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its multifunctional structure, which provides a versatile scaffold for constructing complex molecules with precise stereochemistry. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of protease inhibitors, neurological agents, and other therapeutic compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its stereochemistry can influence biological activity.
• Asymmetric Catalysis: Employed as a precursor or ligand in the development of chiral catalysts for enantioselective synthesis.
• Fine Chemical Production: Serves as a versatile intermediate for creating specialty chemicals, flavors, and fragrances requiring specific chiral centers.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis and medicinal chemistry research within university and corporate laboratories.

Basic Information

Product Name	1-Pyrrolidinecarboxylicacid,2-Cyano-5-Formyl-,Methylester,(2R-Cis)-(9Ci)
CAS No.	178035-98-8
Molecular Formula	C9H10N2O3
Molecular Weight	194.19 g/mol
Synonyms	(2R,5S)-2-Cyano-5-formyl-1-pyrrolidinecarboxylic acid methyl ester; Methyl (2R,5S)-2-cyano-5-formylpyrrolidine-1-carboxylate; (2R,5S)-1-(Methoxycarbonyl)-5-formyl-2-pyrrolidinecarbonitrile; (2R-cis)-2-Cyano-5-formyl-1-pyrrolidinecarboxylic Acid Methyl Ester; 1-Pyrrolidinecarboxylic acid, 2-cyano-5-formyl-, methyl ester, (2R-cis)-; (2R,5S)-1-Methoxycarbonyl-5-formylpyrrolidine-2-carbonitrile
EINECS	Contact for details

Quality Control

Our production of 1-Pyrrolidinecarboxylicacid,2-Cyano-5-Formyl-,Methylester,(2R-Cis)-(9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for advanced synthetic applications. All materials are characterized by modern analytical techniques including HPLC, GC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening to maintain stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.