Description

2-Chloro-5-Fluorophenylacetic Acid is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both chloro and fluoro substituents on the phenyl ring, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted phenylacetic acid moiety.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the fluorine and chlorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in displays and lighting.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, esterifications, and amide bond formations to introduce functionalized aromatic groups into target molecules.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for exploring new synthetic pathways and creating novel compound libraries for screening.

Basic Information

Product Name	2-Chloro-5-Fluorophenylacetic Acid
CAS No.	177985-33-0
Molecular Formula	C8H6ClFO2
Molecular Weight	188.58 g/mol
Synonyms	(2-Chloro-5-fluorophenyl)acetic Acid; 2-Chloro-5-fluorobenzeneacetic Acid; α-(2-Chloro-5-fluorophenyl)acetic Acid; 2-(2-Chloro-5-fluorophenyl)acetic Acid; 2-Chloro-5-fluoro-α-toluic Acid; 2-Chloro-5-fluorophenylacetic Acid; 2-Chloro-5-fluorophenylethanoic Acid; NSC 405124
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Fluorophenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent absorption of atmospheric moisture, which can affect product stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.