Description

2-Chloro-4-Fluorophenylacetic Acid is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its core value lies in its bifunctional structure, featuring both a reactive carboxylic acid group and a halogenated aromatic ring, making it a key intermediate for constructing complex molecules. This compound is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutic agents.
• Agrochemical Synthesis: Serves as a key building block for developing advanced herbicides, fungicides, and pesticides, leveraging the bioactivity of the fluorinated phenylacetic acid structure.
• Liquid Crystal Material Production: Used in the manufacture of fluorinated liquid crystals for display technologies, where the chlorine and fluorine substituents help fine-tune molecular polarity and mesomorphic properties.
• Organic Synthesis Reagent: Functions as a versatile starting material or coupling partner in various organic reactions, including Suzuki, Heck, and esterification reactions.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic pathways and creating specialized chemical libraries.
• Fine Chemical Manufacturing: Utilized in the production of other high-value, specialty fluorinated chemicals and complex organic compounds.

Basic Information

Product Name	2-Chloro-4-Fluorophenylacetic Acid
CAS No.	177985-32-9
Molecular Formula	C8H6ClFO2
Molecular Weight	188.58 g/mol
Synonyms	(2-Chloro-4-fluorophenyl)acetic Acid; 2-Chloro-4-fluorobenzeneacetic Acid; α-(2-Chloro-4-fluorophenyl)acetic Acid; 2-(2-Chloro-4-fluorophenyl)acetic Acid; NSC 405124; 177985-32-9; o-Chloro-p-fluorophenylacetic Acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Fluorophenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in a dark place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.