Description

2,4-Bis(Trifluoromethyl)Phenylacetic Acid is a high-value fluorinated aromatic building block characterized by its electron-deficient phenylacetic acid core flanked by two trifluoromethyl groups. This unique structure makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs) where enhanced lipophilicity, metabolic stability, and electronic properties are required. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in areas requiring fluorinated motifs for improved bioavailability and target binding.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl groups contribute to biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, enhancing their dielectric anisotropy and stability.
• Polymer Modification: Incorporated as a monomer or additive to create specialty polymers with unique surface properties, chemical resistance, and optical characteristics.
• Ligand & Catalyst Development: Utilized in organometallic chemistry to create sophisticated ligands for catalysis, leveraging the strong electron-withdrawing nature of the substituents.
• Advanced Material Research: Employed in academic and industrial R&D for exploring new fluorinated compounds with applications in coatings, sensors, and nanotechnology.

Basic Information

Product Name	2,4-Bis(Trifluoromethyl)Phenylacetic Acid
CAS No.	177952-39-5
Molecular Formula	C10H6F6O2
Molecular Weight	272.15 g/mol
Synonyms	2,4-Bis(trifluoromethyl)benzeneacetic acid; [2,4-Bis(trifluoromethyl)phenyl]acetic acid; α-(2,4-Bis(trifluoromethyl)phenyl)acetic acid; 2-(2,4-Bis(trifluoromethyl)phenyl)acetic acid; 2,4-Di(trifluoromethyl)phenylacetic acid; DTMPA; 2,4-BTFPAA
EINECS	Contact for details

Quality Control

Every batch of 2,4-Bis(Trifluoromethyl)Phenylacetic Acid is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency that meets the stringent requirements of research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to exclude moisture. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.