Description

Pb-Cadherin CAS NO 177646-56-9 is a synthetic peptide sequence designed to mimic the extracellular domain of the human Cadherin-11 protein, specifically for research applications. This compound is a critical tool for investigating cell adhesion mechanisms, signal transduction pathways, and the role of Cadherin-11 in various physiological and pathological processes. It is primarily utilized by researchers and scientists in the fields of cell biology, oncology, and immunology for in vitro studies, assay development, and as a reference standard.

Application

• Biochemical Research: Used as a substrate or inhibitor in studies of cell-cell adhesion and cadherin-mediated signaling pathways.
• Assay Development: Serves as a critical component in ELISA, cell adhesion assays, and other binding studies to quantify interactions.
• Drug Discovery: Employed in high-throughput screening (HTS) platforms to identify potential therapeutic agents that modulate Cadherin-11 activity.
• Antibody Production & Validation: Acts as an immunogen or a positive control for the development and specificity testing of anti-Cadherin-11 antibodies.
• Cancer Research: Investigated for its role in tumor progression, metastasis, and as a potential biomarker in certain cancers.
• Inflammation & Immunology Studies: Explored for its function in inflammatory processes, including rheumatoid arthritis and fibrosis.

Basic Information

Product Name	Pb-Cadherin
CAS No.	177646-56-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cadherin-11 Peptide; CDH11 Peptide; OB-Cadherin Peptide; Osteoblast-Cadherin Peptide; Human Cadherin-11 Fragment; CAS 177646-56-9; PbCad Peptide
EINECS	Contact for details

Quality Control

Our Pb-Cadherin is produced under stringent conditions to ensure the highest standards of purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including mass spectrometry (MS) and high-performance liquid chromatography (HPLC). Certificates of Analysis (COA) detailing purity, identity, and other critical parameters are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70% (by weight)
Solubility	Soluble in water or appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.