Description

2,2-Difluoro-5-Phenyl-Benzo[1,3]Dioxole is a specialized fluorinated heterocyclic compound with the CAS number 177551-64-3. This high-value intermediate is critical for synthesizing advanced materials and active pharmaceutical ingredients (APIs) due to its unique difluoromethylene-dioxole structure. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and advanced polymer industries for developing novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, where the fluorine atoms improve biological activity and environmental stability.
• Advanced Material Precursor: Serves as a monomer or modifier in the production of specialty polymers, coatings, and liquid crystals with tailored optical and electronic properties.
• Organic Electronics: A valuable component in the synthesis of organic semiconductors and light-emitting materials for OLED and OFET applications.
• Chemical Research (R&D): Employed in academic and industrial laboratories as a versatile fluorinated scaffold for exploring new chemical reactions and developing novel synthetic methodologies.

Basic Information

Product Name	2,2-Difluoro-5-Phenyl-Benzo[1,3]Dioxole
CAS No.	177551-64-3
Molecular Formula	C₁₃H₈F₂O₂
Molecular Weight	234.20 g/mol
Synonyms	2,2-Difluoro-5-phenyl-1,3-benzodioxole; 5-Phenyl-2,2-difluorobenzo[d][1,3]dioxole; 2,2-Difluoro-5-phenylbenzo[d][1,3]dioxole; 177551-64-3; Benzo[1,3]dioxole, 2,2-difluoro-5-phenyl-; 5-Phenyl-2,2-difluoro-1,3-benzodioxole
EINECS	Contact for details

Quality Control

Our 2,2-Difluoro-5-Phenyl-Benzo[1,3]Dioxole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.