Description

n-[(1R,3R)-3-Hydroxycyclohexyl]Benzamide is a chiral, stereochemically defined benzamide derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and high-purity building block for the development of novel pharmaceutical intermediates and fine chemicals. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating molecules with specific biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and synthesis of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators where its specific stereochemistry can influence biological efficacy.
• Ligand and Catalyst Development: Acts as a precursor or framework for creating chiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Biochemical Probe Synthesis: Employed in medicinal chemistry to create tool compounds for studying enzyme inhibition and receptor binding.
• Fine Chemical Production: Utilized in custom synthesis and contract manufacturing for producing high-value, specialty chemicals.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic chemistry, including novel cyclization and functionalization reactions.

Basic Information

Product Name	n-[(1R,3R)-3-Hydroxycyclohexyl]Benzamide
CAS No.	177366-90-4
Molecular Formula	C13H17NO2
Molecular Weight	219.28 g/mol
Synonyms	Benzamide, N-[(1R,3R)-3-hydroxycyclohexyl]-; (1R,3R)-3-(Benzoylamino)cyclohexanol; trans-3-Hydroxy-N-(3-hydroxycyclohexyl)benzamide (stereoisomer); (1R,3R)-N-(3-Hydroxycyclohexyl)benzamide; A chiral cyclohexanol benzamide derivative
EINECS	Contact for details

Quality Control

Our n-[(1R,3R)-3-Hydroxycyclohexyl]Benzamide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >97%), enantiomeric excess, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider the use of a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.