Description

tert-Butyl 2-Hydroxy-6-Methylphenylcarbamate is a specialized carbamate derivative, serving as a crucial protected intermediate in advanced organic synthesis. Its primary value lies in enabling the controlled introduction of functional groups, particularly in the synthesis of complex pharmaceutical molecules and agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity building blocks for drug discovery and active ingredient manufacturing.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a protected phenolic amine functionality.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where its structural motif is incorporated into the final active molecule.
• Organic Synthesis Reagent: Serves as a versatile reagent in multi-step synthetic routes for constructing complex heterocycles and other advanced chemical architectures.
• Chemical Research & Development: Employed in academic and industrial R&D laboratories for methodological studies and the development of new synthetic pathways.
• Fine Chemical Production: Acts as a precursor in the manufacture of specialty chemicals, dyes, and performance materials.

Basic Information

Product Name	tert-Butyl 2-Hydroxy-6-Methylphenylcarbamate
CAS No.	177342-60-8
Molecular Formula	C13H19NO3
Molecular Weight	237.29 g/mol
Synonyms	2-Methyl-6-[(tert-butoxycarbonyl)amino]phenol; Carbamic acid, N-(2-hydroxy-6-methylphenyl)-, 1,1-dimethylethyl ester; tert-Butyl N-(2-hydroxy-6-methylphenyl)carbamate; BOC-2-Amino-6-methylphenol; BOC-6-Methylsalicylamide; N-BOC-2-Hydroxy-6-methylaniline; N-(tert-Butoxycarbonyl)-2-hydroxy-6-methylaniline
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Hydroxy-6-Methylphenylcarbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent batch-to-batch quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.