Description

n-(3-Oxotetradecanoyl)-L-Homoserine Lactone is a specialized acylated homoserine lactone (AHL) derivative, a class of compounds widely recognized as signaling molecules in bacterial quorum sensing. This high-purity synthetic intermediate is critical for advanced research and development in microbiology and synthetic biology. It is primarily utilized by researchers in the pharmaceutical and agrochemical industries for studying and modulating bacterial communication pathways, biofilm formation, and virulence.

Application

• Quorum Sensing Research: A key tool for investigating and manipulating bacterial cell-to-cell communication systems in Gram-negative bacteria.
• Anti-virulence Agent Development: Serves as a precursor or reference standard in the synthesis and screening of novel compounds designed to disrupt pathogenic bacterial signaling without inducing resistance.
• Biofilm Studies: Used in academic and industrial labs to study the mechanisms of biofilm formation and to develop anti-biofilm strategies.
• Synthetic Biology: Acts as a crucial building block or signaling molecule in engineered microbial consortia for controlled metabolic pathway regulation.
• Agrochemical Research: Employed in developing next-generation biocontrol agents that target plant pathogens by interfering with their quorum-sensing mechanisms.
• Diagnostic Reagent Synthesis: Used in the preparation of probes and assays for detecting specific bacterial populations based on their signaling profiles.

Basic Information

Product Name	n-(3-Oxotetradecanoyl)-L-Homoserine Lactone
CAS No.	177158-19-9
Molecular Formula	C18H31NO4
Molecular Weight	325.45 g/mol
Synonyms	N-3-Oxotetradecanoyl-L-homoserine lactone; 3-Oxo-C14-HSL; N-(3-Oxotetradecanoyl)-homoserine lactone; 3-Oxotetradecanoyl homoserine lactone; AHL C14-3-oxo; Tetradecan-3-one homoserine lactone derivative; Quorum sensing molecule C14-3-oxo; N-Acyl homoserine lactone (C14, 3-oxo)
EINECS	Contact for details

Quality Control

Every batch of n-(3-Oxotetradecanoyl)-L-Homoserine Lactone is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocol includes advanced chromatographic and spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep at -20°C or below under an inert atmosphere. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation. Store in a cool, dry, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.