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n-[[(1S,8Ar)-2,3,4,5,6,7,8,8A-Octahydro-1H-Quinolizin-1-Yl]Methyl]-2-M Ethoxy-5-Sulfamoyl-Benzamide CAS NO 177027-05-3
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CAS No.:177027-05-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
n-[[(1S,8Ar)-2,3,4,5,6,7,8,8A-Octahydro-1H-Quinolizin-1-Yl]Methyl]-2-M Ethoxy-5-Sulfamoyl-Benzamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new drug candidates.
Application
- Pharmaceutical Intermediate: Key building block in the synthesis of potential new chemical entities (NCEs) for drug discovery programs.
- Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies targeting various biological pathways.
- Active Pharmaceutical Ingredient (API) Development: Serves as a critical intermediate in the multi-step synthesis of complex target molecules for preclinical and clinical evaluation.
- Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
- Academic Research: Utilized in university and institutional labs for exploratory research in organic synthesis and pharmacology.
- Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in API manufacturing.
Basic Information
| Product Name | n-[[(1S,8Ar)-2,3,4,5,6,7,8,8A-Octahydro-1H-Quinolizin-1-Yl]Methyl]-2-M Ethoxy-5-Sulfamoyl-Benzamide |
| CAS No. | 177027-05-3 |
| Molecular Formula | C20H29N3O4S |
| Molecular Weight | 407.53 g/mol |
| Synonyms | N-[(1S,8aR)-Decahydro-2-quinolyl]methyl-2-methoxy-5-sulfamoylbenzamide; 2-Methoxy-5-sulfamoyl-N-[[(1S,8aR)-decahydro-2-quinolyl]methyl]benzamide; (1S,8aR)-N-[(2-Methoxy-5-sulfamoylbenzoyl)amino]methyl]decahydroquinoline; Benzamide, N-[[(1S,8aR)-decahydro-2-quinolyl]methyl]-2-methoxy-5-sulfamoyl-; Decahydroquinoline benzamide derivative; CAS 177027-05-3 |
| EINECS | Contact for details |
Quality Control
Our n-[[(1S,8Ar)-2,3,4,5,6,7,8,8A-Octahydro-1H-Quinolizin-1-Yl]Methyl]-2-M Ethoxy-5-Sulfamoyl-Benzamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or cGMP requirements.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Purity (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 0.5% |
| Residual Solvents (GC) | Complies with ICH guidelines |
| Heavy Metals | ≤ 20 ppm |
| Assay | 97.0% - 102.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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