Description

(R)-Benzyl 1-Cyanoethylcarbamate is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic utility. This compound matters for its role in the stereoselective synthesis of active pharmaceutical ingredients (APIs), particularly in the development of peptidomimetics and other biologically active molecules. It is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries engaged in asymmetric synthesis and drug discovery programs.

Application

• Chiral Intermediate for API Synthesis: A key precursor in the multi-step synthesis of enantiomerically pure pharmaceuticals.
• Peptide & Peptidomimetic Chemistry: Used to introduce chiral, protected amino acid derivatives into peptide chains.
• Asymmetric Synthesis: Serves as a chiral auxiliary or starting material for constructing complex molecular architectures with defined stereochemistry.
• Medicinal Chemistry Research: Employed in the discovery and optimization of new drug candidates, especially protease inhibitors and receptor modulators.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of specialized fine chemicals and advanced intermediates.

Basic Information

Product Name	(R)-Benzyl 1-Cyanoethylcarbamate
CAS No.	176894-58-9
Molecular Formula	C11H12N2O2
Molecular Weight	204.23 g/mol
Synonyms	(R)-Benzyl (1-cyanoethyl)carbamate; (R)-1-Cyanoethyl benzylcarbamate; Carbamic acid, N-[(1R)-1-cyanoethyl]-, phenylmethyl ester; Benzyl N-[(1R)-1-cyanoethyl]carbamate; (R)-Benzyl (α-cyanoethyl)carbamate; (R)-Boc-CN-Et-OBzl (informal); (R)-Cbz-NH-CH(CN)-CH3
EINECS	Contact for details

Quality Control

Our (R)-Benzyl 1-Cyanoethylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.