Description

α-(2,3-Dimethylphenyl)-1-(Trityl)-1H-Imidazole-4-Methanol is a specialized, high-value organic intermediate featuring a unique imidazole core protected by a trityl group. This compound is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of novel pesticides, herbicides, and fungicides where the imidazole moiety imparts specific biological activity.
• Ligand and Catalyst Precursor: Serves as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex organic molecules for material science and electronic chemicals.
• Academic & Institutional Research: Utilized in university and government laboratories for methodological studies in heterocyclic and medicinal chemistry.
• Custom Synthesis & Contract Manufacturing: A vital starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	α-(2,3-Dimethylphenyl)-1-(Trityl)-1H-Imidazole-4-Methanol
CAS No.	176721-01-0
Molecular Formula	C31H28N2O
Molecular Weight	444.57 g/mol
Synonyms	1-(Triphenylmethyl)-α-(2,3-dimethylphenyl)-1H-imidazole-4-methanol; 4-(Hydroxymethyl)-1-tritylimidazole derivative; 1-Trityl-α-(2,3-dimethylphenyl)imidazole-4-methanol; 1H-Imidazole-4-methanol, α-(2,3-dimethylphenyl)-1-(triphenylmethyl)-; (2,3-Dimethylphenyl)[1-(triphenylmethyl)-1H-imidazol-4-yl]methanol; Trityl-protected imidazole methanol derivative; Triphenylmethyl-protected imidazole intermediate
EINECS	Contact for details

Quality Control

Our α-(2,3-Dimethylphenyl)-1-(Trityl)-1H-Imidazole-4-Methanol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports cGMP (current Good Manufacturing Practice) standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.