Description

Cyclobutanecarbonitrile, 1-(Dimethylamino)- (9Ci) is a specialized nitrile derivative featuring a cyclobutane ring and a dimethylamino substituent, serving as a versatile and valuable building block in advanced organic synthesis. Its unique structure makes it a critical intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. This high-purity compound is essential for research and production chemists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific functional groups and ring systems into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of novel drug candidates, particularly those requiring cyclobutane or nitrile functionalities.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where its structural motif can contribute to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced polymers and functional materials with tailored properties.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes to study enzyme mechanisms and biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	Cyclobutanecarbonitrile, 1-(Dimethylamino)- (9Ci)
CAS No.	176445-74-2
Molecular Formula	C7H12N2
Molecular Weight	124.18 g/mol
Synonyms	1-(Dimethylamino)cyclobutanecarbonitrile; 1-(Dimethylamino)cyclobutanenitrile; (1-Cyano-1-cyclobutyl)-N,N-dimethylamine; N,N-Dimethyl-1-cyclobutanecarbonitrile-1-amine; Cyclobutanecarbonitrile, 1-(dimethylamino)-; 1-Cyano-1-cyclobutyl-N,N-dimethylamine; 1-(N,N-Dimethylamino)cyclobutanecarbonitrile
EINECS	Contact for details

Quality Control

Every batch of Cyclobutanecarbonitrile, 1-(Dimethylamino)- (9Ci) is produced and tested under strict quality management systems to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. Our commitment to quality supports compliance with cGMP and ICH guidelines where applicable for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong acids and oxidizing agents. Handle and store under an inert atmosphere if prolonged storage is required to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.