Description

Hcv Ns4A Protein (21-34) (Jt Strain) CAS NO 176260-88-1 is a synthetic peptide fragment corresponding to a specific region of the Hepatitis C Virus (HCV) nonstructural protein 4A. This high-purity biochemical is critical for advanced virology research and diagnostic assay development. It serves as a key antigenic component for antibody production, epitope mapping, and the study of HCV protein-protein interactions, particularly within the viral replication complex. This product is essential for pharmaceutical R&D teams, diagnostic manufacturers, and academic research institutions focused on virology and infectious disease.

Application

• Antigen for Antibody Production: Used as an immunogen to generate specific polyclonal or monoclonal antibodies targeting the HCV NS4A protein.
• Diagnostic Assay Development: Serves as a critical coating antigen or detection reagent in ELISA, immunoblot, and other immunoassays for HCV antibody detection.
• Epitope Mapping & Vaccine Research: Essential for identifying and characterizing B-cell epitopes to support vaccine design and immunogenicity studies.
• Protein-Protein Interaction Studies: Used in biochemical assays to investigate the interaction between NS4A and other viral nonstructural proteins (e.g., NS3 protease) or host cell factors.
• Biochemical Reagent & Positive Control: Acts as a high-quality standard or positive control in research laboratory settings for assay validation and quality assurance.
• Cell Signaling & Virology Research: Employed in fundamental research to understand the role of NS4A in HCV replication, pathogenesis, and host immune response evasion.

Basic Information

Product Name	Hcv Ns4A Protein (21-34) (Jt Strain)
CAS No.	176260-88-1
Molecular Formula	C70H112N20O21S2 (Representative)
Molecular Weight	~1681.9 g/mol (Theoretical)
Synonyms	HCV NS4A (21-34) Peptide; Hepatitis C Virus Nonstructural Protein 4A Fragment 21-34; NS4A (21-34) Peptide (Jt Strain); HCV Peptide Antigen; HCV NS4A Epitope; Synthetic HCV NS4A Peptide; HCV Research Peptide; HCV Diagnostic Antigen
EINECS	Contact for details

Quality Control

This peptide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high biological activity. Each lot is characterized using advanced analytical techniques including HPLC for purity assessment and Mass Spectrometry (MS) for identity confirmation. Certificates of Analysis (COA) detailing purity, peptide content, and analytical data are provided with every shipment to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture absorption. Aliquot into smaller working quantities to minimize freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70% (by weight)
Amino Acid Sequence	H-Gly-Glu-Val-Leu-Leu-Thr-Cys-Ala-Ser-Ile-His-Leu-Pro-Tyr-OH
Single-Letter Sequence	GEVLLTCASIHLPY
Solubility	Soluble in water or aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.