Description

Sodium (R)-α-Lipoate is the sodium salt of the biologically active (R)-enantiomer of α-lipoic acid, a critical cofactor for mitochondrial enzymes. This high-purity form offers superior stability and bioavailability compared to the racemic mixture, making it essential for advanced pharmaceutical and nutraceutical formulations. It is primarily sought by manufacturers in the dietary supplement, cosmeceutical, and pharmaceutical research sectors for its potent antioxidant and metabolic properties.

Application

• Active Pharmaceutical Ingredient (API) in formulations targeting diabetic neuropathy and metabolic syndrome.
• Key raw material in high-end dietary supplements for antioxidant support and cellular energy metabolism.
• Functional ingredient in advanced cosmeceutical products for anti-aging and skin-brightening effects.
• Critical reagent in biochemical research and cell culture studies investigating oxidative stress.
• Intermediate in the synthesis of more complex, enantiomerically pure pharmaceutical compounds.
• Component in specialized parenteral nutrition and injectable formulations.

Basic Information

Product Name	Sodium (R)-α-Lipoate
CAS No.	176110-81-9
Molecular Formula	C8H13NaO2S2
Molecular Weight	228.30 g/mol
Synonyms	Sodium (R)-(+)-Lipoate; (R)-(+)-Thioctic Acid Sodium Salt; Sodium (R)-1,2-Dithiolane-3-pentanoate; (R)-ALA Sodium Salt; R-Lipoic Acid Sodium Salt; (R)-α-Lipoic Acid Sodium Salt; Tiolipon Sodium Salt (R-form); 5-[(3R)-1,2-Dithiolan-3-yl]pentanoic Acid Sodium Salt
EINECS	Contact for details

Quality Control

Our Sodium (R)-α-Lipoate is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical and nutraceutical applications. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing parameters such as enantiomeric purity, assay, and impurity profiles. We support compliance with cGMP, ISO, and relevant pharmacopoeial guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light yellow powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (HPLC)	≥ 99.0% (R-isomer)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.