Description

1,4,7-Tris-Boc-1,4,7,10-Tetraaza-Cyclododecane is a key Boc-protected intermediate in the synthesis of macrocyclic polyamine ligands and chelators. This compound matters for its role in creating sophisticated molecular scaffolds used in medicinal chemistry and diagnostic imaging. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and chemical synthesis sectors for developing targeted therapeutics and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing macrocyclic chelators used in radiopharmaceuticals and MRI contrast agents.
• Ligand Synthesis: Used to prepare functionalized cyclen (1,4,7,10-tetraazacyclododecane) derivatives for metal ion complexation.
• Research & Development: Serves as a protected precursor in academic and industrial R&D for novel catalyst and sensor development.
• Diagnostic Agent Production: Integral to the manufacture of precursors for diagnostic imaging probes utilizing metals like gadolinium or copper.
• Coordination Chemistry: Employed in the study and creation of advanced coordination complexes with specific magnetic or catalytic properties.
• Custom Chemical Synthesis: Used by fine chemical suppliers to produce tailored polyamine compounds for client-specific applications.

Basic Information

Product Name	1,4,7-Tris-Boc-1,4,7,10-Tetraaza-Cyclododecane
CAS No.	175854-39-4
Molecular Formula	C25H46N4O6
Molecular Weight	498.66 g/mol
Synonyms	1,4,7-Tris(tert-butoxycarbonyl)-1,4,7,10-tetraazacyclododecane; 1,4,7-Tri-Boc-1,4,7,10-tetraazacyclododecane; Tris-Boc-cyclen; 1,4,7-Tris-Boc-cyclen; 1,4,7-Tris(tert-butyloxycarbonyl)-1,4,7,10-tetraazacyclododecane; 1,4,7-Tri-Boc-cyclen; 1,4,7-Tris-Boc-tetraazacyclododecane; 1,4,7-Tri-tert-butoxycarbonyl-1,4,7,10-tetraazacyclododecane
EINECS	Contact for details

Quality Control

Our 1,4,7-Tris-Boc-1,4,7,10-Tetraaza-Cyclododecane undergoes rigorous quality testing to ensure compliance with industry standards for high-purity intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We adhere to strict in-process controls to guarantee batch-to-batch consistency and reliability for your synthetic workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.