Description

2，2-Difluoro-2-(3-(Trifluoromethyl)Phenyl)Acetic Acid is a high-value fluorinated aromatic building block characterized by its unique difluoroacetic acid moiety attached to a trifluoromethylphenyl ring. This compound is essential for introducing multiple fluorine atoms into target molecules, significantly altering their physicochemical properties such as metabolic stability, lipophilicity, and bioavailability. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in oncology, CNS, and antiviral therapeutic areas.
• Agrochemical Synthesis: Used to create advanced herbicides, fungicides, and insecticides where fluorination enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display technologies and organic light-emitting diodes.
• Polymer Modification: Incorporated into specialty polymers to impart unique chemical resistance, thermal stability, and surface properties.
• Advanced Material Research: Employed in academic and industrial R&D for creating novel fluorinated compounds with tailored properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	2，2-Difluoro-2-(3-(Trifluoromethyl)Phenyl)Acetic Acid
CAS No.	175543-27-8
Molecular Formula	C9H5F5O2
Molecular Weight	240.13 g/mol
Synonyms	2,2-Difluoro-2-[3-(trifluoromethyl)phenyl]acetic acid; α,α-Difluoro-3-(trifluoromethyl)benzeneacetic acid; 3-(Trifluoromethyl)benzeneacetic acid, α,α-difluoro-; 2,2-Difluoro-2-(3-trifluoromethylphenyl)acetic Acid; [3-(Trifluoromethyl)phenyl]difluoroacetic Acid; (3-Trifluoromethylphenyl)difluoroacetic Acid
EINECS	Contact for details

Quality Control

Our 2，2-Difluoro-2-(3-(Trifluoromethyl)Phenyl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.