Description

Ethyl 2,2-Difluoro-2-(4-Fluorophenyl)Acetate is a high-purity fluorinated organic ester, serving as a critical building block in advanced chemical synthesis. Its value lies in the unique reactivity imparted by the difluoroacetate moiety, which is essential for constructing complex molecules with specific properties. This intermediate is primarily sought by research and development teams and production chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly those requiring a difluoroacetate or fluorinated phenyl group.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where fluorine substitution enhances biological activity and stability.
• Material Science Research: Serves as a precursor for fluorinated monomers or additives aimed at modifying polymer properties like solvent resistance or surface energy.
• Liquid Crystal & Electronic Chemicals: Potential building block for fluorinated components in display materials or dielectric fluids.
• Organic Synthesis & Process Chemistry: A versatile reagent for introducing the 2,2-difluoro-2-(4-fluorophenyl)acetyl fragment into target molecules in laboratory and pilot-scale reactions.

Basic Information

Product Name	Ethyl 2,2-Difluoro-2-(4-Fluorophenyl)Acetate
CAS No.	175543-23-4
Molecular Formula	C10H9F3O2
Molecular Weight	218.17 g/mol
Synonyms	Ethyl 4-Fluoro-α,α-difluorobenzeneacetate; 2,2-Difluoro-2-(4-fluorophenyl)acetic Acid Ethyl Ester; Ethyl (4-Fluorophenyl)difluoroacetate; 4-Fluoro-α,α-difluorobenzeneacetic Acid Ethyl Ester; Ethyl α,α-Difluoro-4-fluorophenylacetate; 175543-23-4; Acetic acid, 2,2-difluoro-2-(4-fluorophenyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Every batch of Ethyl 2,2-Difluoro-2-(4-Fluorophenyl)Acetate is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. A comprehensive Certificate of Analysis (COA), detailing purity, identity, and impurity profiles, is provided with each shipment to guarantee consistency and support your quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.