Description

n-Boc-2-Methylbenzimidazole CAS NO 175531-34-7 is a protected benzimidazole derivative, a crucial building block in modern organic synthesis. Its value lies in the tert-butoxycarbonyl (Boc) protecting group, which safeguards the imidazole nitrogen during multi-step reactions, enabling the precise construction of complex molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, especially those targeting various receptors and enzymes.
• Agrochemical Synthesis: Used in the research and production of advanced fungicides, herbicides, and plant growth regulators.
• Peptidomimetics & Heterocyclic Chemistry: Serves as a protected scaffold for constructing complex heterocyclic systems and peptide-like molecules.
• Material Science Research: Employed in the development of organic semiconductors, ligands for catalysis, and specialty polymers.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring high-fidelity nitrogen protection.
• Academic & R&D Laboratories: Used in medicinal chemistry and synthetic methodology research for exploring new chemical entities.

Basic Information

Item	Details
Product Name	n-Boc-2-Methylbenzimidazole
CAS No.	175531-34-7
Molecular Formula	C₁₃H₁₆N₂O₂
Molecular Weight	232.28 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-2-methyl-1H-benzimidazole; tert-Butyl 2-methyl-1H-benzimidazole-1-carboxylate; 2-Methyl-1H-benzimidazole-1-carboxylic acid tert-butyl ester; 1-Boc-2-methylbenzimidazole; N-Boc-2-methylbenzimidazole; 1-(tert-Butyloxycarbonyl)-2-methylbenzimidazole; 2-Methylbenzimidazole-1-N-Boc; 1-N-Boc-2-methylbenzimidazole
EINECS	Contact for details

Quality Control

Our n-Boc-2-Methylbenzimidazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.