Description

Benzamide, 2-Hydroxy-n-(6-(Hydroxymethyl)-2,5-Dioxo-7-Oxabicyclo(4.1.0 )Hept-3-En-3-Yl)-, (1S)- is a high-purity, stereochemically defined bicyclic compound that serves as a critical advanced intermediate in complex organic syntheses. Its unique molecular architecture, featuring a fused oxabicycloheptene core with multiple functional handles, makes it an invaluable building block for the development of novel active pharmaceutical ingredients (APIs) and specialty fine chemicals. This product is essential for research and production teams in pharmaceutical development, agrochemical research, and advanced material science who require precise, high-quality chiral intermediates to drive innovation.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of complex drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of novel, high-efficacy pesticides and herbicides due to its reactive bicyclic structure.
• Chemical Biology Probe Development: Serves as a core scaffold for creating molecular probes to study enzyme function and biological pathways.
• Advanced Material Synthesis: Building block for polymers and functional materials requiring specific stereochemistry and thermal properties.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial manufacturing of complex molecules.
• Academic & Institutional Research: Used in university and R&D lab settings for methodological development in asymmetric synthesis and heterocyclic chemistry.

Basic Information

Product Name	Benzamide, 2-Hydroxy-n-(6-(Hydroxymethyl)-2,5-Dioxo-7-Oxabicyclo(4.1.0 )Hept-3-En-3-Yl)-, (1S)-
CAS No.	175448-32-5
Molecular Formula	C15H13NO6
Molecular Weight	303.27 g/mol
Synonyms	(1S)-2-Hydroxy-N-[6-(hydroxymethyl)-2,5-dioxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]benzamide; (1S)-rel-(1S,6R)-3-[(2-Hydroxybenzoyl)amino]-6-(hydroxymethyl)-7-oxabicyclo[4.1.0]hept-3-ene-2,5-dione; 7-Oxabicyclo[4.1.0]hept-3-ene-2,5-dione, 3-[(2-hydroxybenzoyl)amino]-6-(hydroxymethyl)-, (1S,6R)-rel-; Bicyclic Benzamide Derivative; Oxanorbornene Benzamide Intermediate
EINECS	Contact for details

Quality Control

Every batch of our Benzamide, 2-Hydroxy-n-(6-(Hydroxymethyl)-2,5-Dioxo-7-Oxabicyclo(4.1.0 )Hept-3-En-3-Yl)-, (1S)- is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity, NMR for structural confirmation, and stringent control of residual solvents and impurities to meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and assay is provided with each shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.