Description

Dl-Asparagine Ethyl Ester Dihydrochloride is a protected amino acid derivative, specifically the ethyl ester hydrochloride salt of DL-asparagine. This compound is a crucial building block in organic synthesis and peptide chemistry, offering enhanced solubility and reactivity for controlled coupling reactions. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the development of novel peptides, bioactive molecules, and advanced intermediates.

Application

• Peptide Synthesis: Serves as a key protected asparagine residue in solid-phase and solution-phase peptide synthesis (SPPS).
• Pharmaceutical Intermediates: Used in the research and development of potential drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Acts as a substrate or precursor in enzymatic studies and metabolic pathway investigations.
• Fine Chemical Production: Employed as a chiral synthon for the asymmetric synthesis of complex organic molecules.
• Protecting Group Strategy: The ethyl ester and hydrochloride salt forms provide orthogonal protection for the amino and carboxyl groups during multi-step syntheses.

Basic Information

Product Name	Dl-Asparagine Ethyl Ester Dihydrochloride
CAS No.	175414-76-3
Molecular Formula	C6H13N2O3 · 2HCl
Molecular Weight	241.10 g/mol (Free base: 173.18 g/mol)
Synonyms	DL-Asparagine ethyl ester dihydrochloride; Ethyl DL-asparaginate dihydrochloride; (±)-2-Amino-3-carbamoylpropanoic acid ethyl ester hydrochloride; H-Asn-OEt · 2HCl; DL-Asn-OEt · 2HCl; Asparagine ethyl ester HCl; NSC 760443
EINECS	Contact for details

Quality Control

Our Dl-Asparagine Ethyl Ester Dihydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	± 0.5° (c=1 in H2O)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.