Description

1,5-Cyclohexadiene-1,4-Diol,3,5-Difluoro-(9Ci) is a specialized fluorinated diol derivative of cyclohexadiene, serving as a high-value synthetic intermediate. Its unique structure, featuring both fluorine atoms and hydroxyl groups on a conjugated diene system, makes it a critical building block for advanced material and pharmaceutical research. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel fluorinated active pharmaceutical ingredients (APIs) and drug candidates, leveraging fluorine's metabolic stability and bioavailability-enhancing properties.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides where the fluorinated diol moiety can improve efficacy and environmental profile.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers, coatings, and resins with tailored thermal, chemical, or surface properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry for creating chiral ligands or metal-organic frameworks (MOFs) used in asymmetric catalysis and separation technologies.
• Fluorine Chemistry Research: A valuable substrate for studying novel fluorination reactions, ring-opening polymerizations, and Diels-Alder cycloadditions in academic and industrial R&D settings.

Basic Information

Product Name	1,5-Cyclohexadiene-1,4-Diol,3,5-Difluoro-(9Ci)
CAS No.	175359-13-4
Molecular Formula	C6H6F2O2
Molecular Weight	148.11 g/mol
Synonyms	3,5-Difluoro-1,4-cyclohexadiene-1,4-diol; 3,5-Difluorocyclohexa-1,4-diene-1,4-diol; 1,4-Cyclohexadiene-1,4-diol, 3,5-difluoro-; 1,4-Dihydroxy-3,5-difluorobenzene (tautomer); 3,5-Difluoro-1,4-dihydroxybenzene; 3,5-Difluororesorcinol (common name); 3,5-Difluoro-1,4-benzenediol
EINECS	Contact for details

Quality Control

Our 1,5-Cyclohexadiene-1,4-Diol,3,5-Difluoro-(9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as identity, assay, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for reliable sourcing of advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single unknown impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.