Description

4-Cyano-2-(Trifluoromethoxy)Acetanilide is a specialized organic intermediate featuring a unique combination of cyano and trifluoromethoxy functional groups on an acetanilide backbone. This compound is valued for its role as a critical building block in the synthesis of advanced pharmaceutical and agrochemical agents. It is primarily sought by research and development chemists, process development scientists, and manufacturers in the fine chemical and life science industries for creating novel molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a building block for designing chemical probes, enzyme inhibitors, and labeled compounds for biochemical assays and diagnostic research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and contract research organizations (CROs/CMOs) developing proprietary compounds for clients.

Basic Information

Product Name	4-Cyano-2-(Trifluoromethoxy)Acetanilide
CAS No.	175278-19-0
Molecular Formula	C10H7F3N2O2
Molecular Weight	244.17 g/mol
Synonyms	N-(4-Cyano-2-(trifluoromethoxy)phenyl)acetamide; 2'-Trifluoromethoxy-4'-cyanoacetanilide; Acetamide, N-[4-cyano-2-(trifluoromethoxy)phenyl]-; 4-Cyano-2-trifluoromethoxyacetanilide; 4-Acetamido-3-(trifluoromethoxy)benzonitrile; 175278-19-0; 4-Cyano-2-(trifluoromethoxy)phenylacetamide
EINECS	Contact for details

Quality Control

Our 4-Cyano-2-(Trifluoromethoxy)Acetanilide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and moisture. For long-term storage, consider using desiccants to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.