Description

2,3,4-Trifluorobenzenesulfonyl Chloride is a versatile and highly reactive organofluorine building block. This compound is a critical intermediate for the synthesis of advanced materials and active pharmaceutical ingredients (APIs), valued for its ability to introduce the sulfonyl chloride functional group into complex fluorinated aromatic systems. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the trifluoromethyl and sulfonyl groups enhance biological activity and environmental stability.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers, membranes, and liquid crystals with unique thermal and chemical resistance.
• Chemical Research: Essential reagent in organic synthesis for introducing the benzenesulfonyl moiety, facilitating further functionalization in fluorinated aromatic chemistry.
• Dye and Pigment Manufacturing: Intermediate for creating sulfonated fluorinated dyes with improved color fastness and solubility properties.

Basic Information

Product Name	2,3,4-Trifluorobenzenesulfonyl Chloride
CAS No.	175278-08-7
Molecular Formula	C6H2ClF3O2S
Molecular Weight	230.59 g/mol
Synonyms	2,3,4-Trifluorobenzene-1-sulfonyl chloride; 1-(Chlorosulfonyl)-2,3,4-trifluorobenzene; 2,3,4-Trifluorophenylsulfonyl chloride; Benzenesulfonyl chloride, 2,3,4-trifluoro-; 2,3,4-Trifluoro-1-sulfonylchlorobenzene; 2,3,4-Trifluorobenzenesulphonyl chloride
EINECS	Contact for details

Quality Control

Our 2,3,4-Trifluorobenzenesulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and industrial synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.