Description

1-[3,5-Bis(Trifluoromethyl)Phenyl]-2-Thiourea is a high-value organofluorine thiourea derivative, a key building block in advanced chemical synthesis. Its unique structure, featuring electron-withdrawing trifluoromethyl groups, makes it an essential reagent for creating complex molecules with tailored properties. This compound is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical industries for applications in catalysis, medicinal chemistry, and material science.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of biologically active molecules, particularly for drug discovery programs targeting enzyme inhibition.
• Catalyst Ligand: Serves as a ligand or co-catalyst in transition metal-catalyzed reactions, including cross-coupling and C-H activation processes.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the trifluoromethyl group enhances bioavailability and stability.
• Material Science Research: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probe: Utilized as a molecular tool to study protein interactions and enzyme mechanisms due to its thiourea moiety.

Basic Information

Product Name	1-[3,5-Bis(Trifluoromethyl)Phenyl]-2-Thiourea
CAS No.	175277-17-5
Molecular Formula	C9H5F6N2S
Molecular Weight	278.21 g/mol
Synonyms	N-[3,5-Bis(trifluoromethyl)phenyl]thiourea; 1-[3,5-Bis(trifluoromethyl)phenyl]thiourea; 3,5-Bis(trifluoromethyl)phenylthiourea; α,α,α,α',α',α'-Hexafluoro-3,5-xylylene thiourea; Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-; 3,5-Di(trifluoromethyl)phenylthiourea; 1-(3,5-Bis(trifluoromethyl)phenyl)-2-thiourea
EINECS	Contact for details

Quality Control

Every batch of 1-[3,5-Bis(Trifluoromethyl)Phenyl]-2-Thiourea is produced and tested under strict quality management protocols to ensure consistency and high purity. Our products undergo rigorous quality testing, including HPLC and NMR analysis, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.