Description

2-Phenyl-2-(Trifluoroacetyl)Acetonitrile is a specialized fluorinated organic building block of significant interest in advanced chemical synthesis. This compound matters for its unique trifluoroacetyl and nitrile functional groups, which enable precise molecular construction in demanding applications. It is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex molecules, particularly those requiring the introduction of a trifluoromethyl group for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in developing new active ingredients for crop protection, where the fluorine atoms can improve pesticidal activity and environmental profile.
• Fluorine Chemistry: Serves as a versatile synthon for constructing fluorinated heterocycles, such as pyrazoles and isoxazoles, which are valuable scaffolds in medicinal chemistry.
• Material Science: Potential building block for specialty polymers and advanced materials where fluorine content can impart unique properties like chemical resistance or low surface energy.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of novel chemical entities for client projects.

Basic Information

Product Name	2-Phenyl-2-(Trifluoroacetyl)Acetonitrile
CAS No.	175205-70-6
Molecular Formula	C11H6F3NO
Molecular Weight	225.16 g/mol
Synonyms	2-Phenyl-2-(trifluoroacetyl)acetonitrile; 2-Oxo-4-phenyl-4-(trifluoromethyl)butanenitrile; 4-Phenyl-4-(trifluoromethyl)-3-oxobutanenitrile; α-Phenyl-α-(trifluoroacetyl)acetonitrile; 3-Oxo-2-phenyl-4,4,4-trifluorobutanenitrile; Benzeneacetonitrile, α-(trifluoroacetyl)-; (Trifluoroacetyl)(phenyl)acetonitrile
EINECS	Contact for details

Quality Control

Our 2-Phenyl-2-(Trifluoroacetyl)Acetonitrile is produced and tested under a rigorous quality management system. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (by HPLC), impurity profile, and physical properties are provided and available upon request, supporting your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.