Description

4-Chloro-3-Cyano-6-Fluoro-2H-Benzopyran is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring chloro, cyano, and fluoro substituents on a benzopyran scaffold, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine and chlorine atoms can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for the synthesis of specialty polymers, liquid crystals, or organic electronic materials due to its rigid, functionalized structure.
• Chemical Biology Probes: Employed in the design and synthesis of fluorescent dyes, tags, or molecular probes for diagnostic and research applications.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting exploratory synthetic chemistry and methodology development.

Basic Information

Product Name	4-Chloro-3-Cyano-6-Fluoro-2H-Benzopyran
CAS No.	175205-57-9
Molecular Formula	C10H5ClFNO
Molecular Weight	209.61 g/mol
Synonyms	4-Chloro-6-fluoro-2H-1-benzopyran-3-carbonitrile; 6-Fluoro-4-chloro-2H-chromene-3-carbonitrile; 4-Chloro-3-cyano-6-fluorochromene; 4-Chloro-6-fluoro-3-cyano-2H-chromene; 4-Chloro-6-fluoro-2H-chromene-3-carbonitrile; 175205-57-9; 4-Chloro-6-fluoro-2H-1-benzopyran-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Cyano-6-Fluoro-2H-Benzopyran is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) detailing all specifications is supplied with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.