Description

2-Chloro-4-(Trifluoromethyl)Benzenesulfonyl Chloride is a versatile and high-value sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value proposition lies in its dual reactive sites, enabling the efficient introduction of the sulfonyl group and facilitating the creation of complex molecules with tailored properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active ingredients and functional materials.

Application

This sulfonyl chloride is a key synthetic intermediate with broad utility across several high-tech sectors.

• Pharmaceutical Intermediate: Core building block for the synthesis of sulfonamide-based drugs, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that leverage the sulfonyl moiety for enhanced bioactivity.
• Dyestuff and Pigment Production: Acts as a precursor for sulfonated dyes and pigments, improving solubility and color fastness.
• Polymer Chemistry: Employed in the synthesis of specialty polymers and functional materials, such as sulfonated polymers for ion-exchange membranes.
• Chemical Research & Development: A valuable reagent in medicinal chemistry and material science for structure-activity relationship (SAR) studies and novel compound library generation.

Basic Information

Product Name	2-Chloro-4-(Trifluoromethyl)Benzenesulfonyl Chloride
CAS No.	175205-54-6
Molecular Formula	C7H3Cl2F3O2S
Molecular Weight	278.06 g/mol
Synonyms	2-Chloro-α,α,α-trifluoro-p-toluenesulfonyl chloride; 4-Chloro-α,α,α-trifluoro-o-toluenesulfonyl chloride; 2-Chloro-4-(trifluoromethyl)benzene-1-sulfonyl chloride; Benzenesulfonyl chloride, 2-chloro-4-(trifluoromethyl)-; 2-Chloro-α,α,α-trifluoro-p-tolylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our production of 2-Chloro-4-(Trifluoromethyl)Benzenesulfonyl Chloride adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, identity, and impurity profiles to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.