Description

5-[3-(Trifluoromethyl)Phenyl]Oxazole is a specialized heterocyclic organic compound featuring an oxazole ring linked to a trifluoromethyl-substituted phenyl group. This structure is highly valued for its role as a critical synthetic intermediate in advanced organic chemistry and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules with tailored properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or functional component in the creation of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a scaffold for designing enzyme inhibitors or receptor modulators.
• Fluorine Chemistry: Acts as a versatile substrate for further functionalization, leveraging the reactivity of the oxazole ring and the fluorine atoms for introducing new chemical diversity.

Basic Information

Product Name	5-[3-(Trifluoromethyl)Phenyl]Oxazole
CAS No.	175205-48-8
Molecular Formula	C10H6F3NO
Molecular Weight	213.16 g/mol
Synonyms	5-(3-(Trifluoromethyl)phenyl)oxazole; 3-(Oxazol-5-yl)benzotrifluoride; 5-(α,α,α-Trifluoro-m-tolyl)oxazole; 5-(m-Trifluoromethylphenyl)oxazole; Oxazole, 5-[3-(trifluoromethyl)phenyl]-; 175205-48-8; 5-(3-Trifluoromethylphenyl)-1,3-oxazole
EINECS	Contact for details

Quality Control

Our production of 5-[3-(Trifluoromethyl)Phenyl]Oxazole adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR) against established internal specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.