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4-Acetamido-4'-Maleimidylstilbene-2,2'-Disulfonic Acid, Disodium Salt CAS NO 175171-43-4


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CAS No.:175171-43-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Acetamido-4'-Maleimidylstilbene-2,2'-Disulfonic Acid, Disodium Salt is a specialized, high-purity chemical intermediate featuring a reactive maleimide group and a stilbene-based fluorescent scaffold. This compound matters for its unique bifunctional reactivity, enabling precise conjugation and labeling in advanced research and development. It is primarily needed by scientists and manufacturers in the pharmaceutical, bioconjugation, and life science reagent sectors for developing fluorescent probes, protein labeling kits, and diagnostic assays.

Application

  • Bioconjugation Reagent: For site-specific labeling of proteins, antibodies, and peptides via the reactive maleimide group.
  • Fluorescent Probe Synthesis: Serves as a key building block for creating environment-sensitive fluorescent sensors and molecular beacons.
  • Diagnostic Assay Development: Used in the formulation of fluorescent detection systems for immunoassays and nucleic acid analysis.
  • Protein Interaction Studies: Enables Förster Resonance Energy Transfer (FRET)-based studies to investigate protein-protein interactions.
  • Material Science Research: Acts as a functional monomer or crosslinker in the development of advanced polymeric materials with optical properties.
  • Chemical Biology Tool: Utilized for tracking and visualizing biological processes in cellular and biochemical research.

Basic Information

Product Name 4-Acetamido-4'-Maleimidylstilbene-2,2'-Disulfonic Acid, Disodium Salt
CAS No. 175171-43-4
Molecular Formula C21H15N2Na2O10S2
Molecular Weight 556.45 g/mol
Synonyms 4-Acetamido-4'-maleimidostilbene-2,2'-disulfonic acid disodium salt; AMS disodium salt; 4-Acetamido-4'-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)stilbene-2,2'-disulfonic acid disodium salt; 1-[4'-(2-Carboxyvinyl)-3-sulfophenyl]-2,5-pyrroledione, 4'-acetamido-2-sulfodisodium salt; Maleimide stilbene disulfonate derivative; Fluorescent maleimide crosslinker; Bifunctional stilbene reagent.
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Quality Control

Our 4-Acetamido-4'-Maleimidylstilbene-2,2'-Disulfonic Acid, Disodium Salt is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment and handled under appropriate conditions to maintain stability and purity.

Specification

Item Specification
Appearance Yellow to orange powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Heavy Metals ≤ 20 ppm
Solubility Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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