Description

2'-Bromo-4'-(Trifluoromethyl)Acetanilide 98 is a high-purity, halogenated aniline derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the strategic combination of bromine and trifluoromethyl functional groups, enabling precise molecular construction and the introduction of desirable physicochemical properties. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is utilized in the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Precursor: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials due to its unique electronic properties.
• Cross-Coupling Reactions: Serves as a versatile substrate in palladium-catalyzed reactions, such as Suzuki and Buchwald-Hartwig couplings, for creating complex biaryl structures.
• Chemical Research & Development: A valuable reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies to optimize lead compounds.
• Fluorine Chemistry: Acts as a source of a trifluoromethylated aromatic moiety for introducing fluorine atoms into target molecules to modulate lipophilicity and metabolic stability.

Basic Information

Product Name	2'-Bromo-4'-(Trifluoromethyl)Acetanilide 98
CAS No.	175135-49-6
Molecular Formula	C9H7BrF3NO
Molecular Weight	282.06 g/mol
Synonyms	N-(2-Bromo-4-(trifluoromethyl)phenyl)acetamide; 2-Bromo-4-(trifluoromethyl)acetanilide; 2'-Bromo-α,α,α-trifluoro-p-acetotoluidide; Acetamide, N-[2-bromo-4-(trifluoromethyl)phenyl]-; 2-Bromo-4-trifluoromethylacetanilide; N-(2-Bromo-4-trifluoromethylphenyl)acetamide
EINECS	Contact for details

Quality Control

Our 2'-Bromo-4'-(Trifluoromethyl)Acetanilide 98 is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. The container should be kept tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.