Description

trans-(4-Aminomethyl-Cyclohexylmethyl)-Carbamic Acid tert-Butyl Ester is a high-purity, protected amine derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in providing a chemically stable and versatile scaffold for constructing complex molecules with precise stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel drug candidates, including protease inhibitors and other biologically active molecules.
• Peptidomimetics Research: Used to introduce constrained cyclohexyl-based amino acid analogs into peptide backbones to enhance metabolic stability and binding affinity.
• Agrochemical Synthesis: Building block for creating advanced crop protection agents with specific stereochemical requirements for efficacy.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis.
• Custom Chemical Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects.
• Academic Research: Utilized in university and institutional labs for methodological development in stereoselective synthesis.

Basic Information

Product Name	trans-(4-Aminomethyl-Cyclohexylmethyl)-Carbamic Acid tert-Butyl Ester
CAS No.	174959-91-2
Molecular Formula	C13H26N2O2
Molecular Weight	242.36 g/mol
Synonyms	trans-4-(Aminomethyl)cyclohexanemethylcarbamic Acid tert-Butyl Ester; (trans-4-Aminomethyl-cyclohexylmethyl)-carbamic Acid tert-Butyl Ester; tert-Butyl N-[(trans-4-(aminomethyl)cyclohexyl)methyl]carbamate; Boc-trans-4-(Aminomethyl)cyclohexylmethanamine; Boc-Amc-OH; (1r,4r)-4-(Aminomethyl)cyclohexyl)methylcarbamic Acid tert-Butyl Ester; trans-N-Boc-1,4-cyclohexanedimethanamine; 174959-91-2
EINECS	Contact for details

Quality Control

Our trans-(4-Aminomethyl-Cyclohexylmethyl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring compliance with research and development standards. Comprehensive Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.