Description

n-[(4-Aminophenyl)Methyl]Carbamic Acid 1,1-Dimethylethyl Ester Hydrochloride is a protected amine derivative, specifically a tert-butyloxycarbonyl (Boc) protected aniline, supplied as its hydrochloride salt. This compound serves as a crucial high-purity building block in organic synthesis, offering a stable and reactive intermediate for constructing complex molecular architectures. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams for the development of active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of novel drug candidates, particularly those containing aniline or benzylamine pharmacophores.
• Peptide & Protein Research: Used in solid-phase peptide synthesis (SPPS) as a protected amino acid derivative for introducing specific functional groups.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced herbicides, fungicides, and plant growth regulators.
• Dye & Pigment Manufacturing: Acts as an intermediate for synthesizing complex azo dyes and high-performance pigments.
• Polymer Science: Employed in the creation of specialty polymers and functional materials requiring aromatic amine linkages.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for biochemical and diagnostic research.

Basic Information

Product Name	n-[(4-Aminophenyl)Methyl]Carbamic Acid 1,1-Dimethylethyl Ester Hydrochloride
CAS No.	174959-54-7
Molecular Formula	C12H19ClN2O2
Molecular Weight	258.75 g/mol
Synonyms	4-(Boc-Aminomethyl)aniline Hydrochloride; N-Boc-4-Aminobenzylamine Hydrochloride; tert-Butyl (4-Aminobenzyl)carbamate Hydrochloride; 1,1-Dimethylethyl N-[(4-Aminophenyl)methyl]carbamate Hydrochloride; Boc-4-Abz-NH2·HCl; (4-Aminobenzyl)carbamic Acid tert-Butyl Ester Hydrochloride; 4-(Boc-aminomethyl)phenylamine HCl
EINECS	Contact for details

Quality Control

Our production of n-[(4-Aminophenyl)Methyl]Carbamic Acid 1,1-Dimethylethyl Ester Hydrochloride adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested against rigorous internal specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support compliance requirements for cGMP and ISO 9001 standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%; Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.