Description

(S)-2-Hydroxy-2,4-Dimethyl-Pentanenitrile is a chiral, high-purity nitrile derivative characterized by its stereogenic center and hydroxyl functionality. This compound serves as a versatile and valuable chiral building block in advanced organic synthesis, enabling the construction of complex molecules with precise stereochemistry. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs), particularly for neurological and metabolic drugs.
• Agrochemical Synthesis: Used in the research and production of chiral herbicides, fungicides, and plant growth regulators requiring specific stereoisomers for optimal activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where optical purity is critical.
• Academic and Process Chemistry Research: A valuable reagent for methodological studies in asymmetric synthesis and scale-up process optimization.

Basic Information

Product Name	(S)-2-Hydroxy-2,4-Dimethyl-Pentanenitrile
CAS No.	174849-23-1
Molecular Formula	C7H13NO
Molecular Weight	127.18 g/mol
Synonyms	(S)-2,4-Dimethyl-2-hydroxypentanenitrile; (2S)-2-Hydroxy-2,4-dimethylpentanenitrile; (S)-2-Hydroxy-2,4-dimethylvaleronitrile; Pentanenitrile, 2-hydroxy-2,4-dimethyl-, (2S)-; (S)-2,4-Dimethyl-2-hydroxyvaleronitrile; (S)-α-Hydroxyisocapronitrile; (S)-2-Hydroxy-2,4-dimethylpentanenitrile
EINECS	Contact for details

Quality Control

Our (S)-2-Hydroxy-2,4-Dimethyl-Pentanenitrile is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.