Description

3-Morpholinone,2-Hydroxy-4-Methyl-,(S)-(9Ci) CAS NO 174746-93-1 is a chiral, substituted morpholinone derivative that serves as a valuable pharmaceutical intermediate and building block in organic synthesis. Its significance lies in its stereochemistry and functional groups, which enable the construction of complex molecules with high enantiomeric purity. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral building block in the synthesis of novel therapeutic agents, particularly for central nervous system (CNS) and anti-infective drugs.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Agrochemical Research: Used in the development of enantiomerically pure pesticides and herbicides for enhanced efficacy and environmental safety.
• Material Science: Serves as a monomer or precursor for synthesizing specialized polymers and functional materials with tailored properties.
• Academic & R&D: A crucial reagent in medicinal chemistry research for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Process Chemistry: Utilized in scale-up and route development for the commercial manufacturing of chiral compounds.

Basic Information

Product Name	3-Morpholinone,2-Hydroxy-4-Methyl-,(S)-(9Ci)
CAS No.	174746-93-1
Molecular Formula	C5H9NO3
Molecular Weight	131.13 g/mol
Synonyms	(S)-2-Hydroxy-4-methyl-3-morpholinone; (S)-4-Methyl-2-hydroxy-3-morpholinone; (3S)-2-Hydroxy-4-methyl-3-morpholinone; (S)-4-Methyl-2,3-dihydro-1,4-oxazin-3-one; 2-Hydroxy-4-methyl-3-morpholinone, (S)-; L-2-Hydroxy-4-methyl-3-morpholinone; (S)-HMM
EINECS	Contact for details

Quality Control

Our production of 3-Morpholinone,2-Hydroxy-4-Methyl-,(S)-(9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC, NMR, and Karl Fischer titration. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. Our quality system is designed to support cGMP requirements for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.