Description

(1S,2S)-N,n-Bis[2-(Diphenylphosphino)Benzyl]Cyclohexane-1,2-Diamine, Min. 97% is a high-purity, chiral diphosphine-diamine hybrid ligand, a critical component in advanced asymmetric catalysis. This compound matters for its exceptional ability to induce high enantioselectivity and catalytic activity in transition metal complexes, enabling the synthesis of complex chiral molecules with precision. It is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-performance ligands for challenging asymmetric transformations.

Application

• Asymmetric Hydrogenation: A premier ligand for the enantioselective reduction of prochiral olefins, ketones, and imines, crucial for producing single-enantiomer pharmaceutical intermediates.
• Asymmetric C-C Bond Formation: Used in cross-coupling reactions, allylic alkylations, and other metal-catalyzed C-C bond constructions to create chiral centers with high fidelity.
• Pharmaceutical Intermediate Synthesis: Enables the production of optically pure active pharmaceutical ingredients (APIs) for drugs targeting CNS disorders, cardiovascular diseases, and infectious diseases.
• Agrochemical Synthesis: Facilitates the creation of enantiomerically pure herbicides, fungicides, and pesticides with improved efficacy and environmental profiles.
• Fine Chemical and Fragrance Production: Applied in the synthesis of complex chiral molecules for flavors, fragrances, and specialty materials.
• Academic and Industrial R&D: Serves as a key tool for developing new catalytic methodologies and exploring novel reaction pathways in process chemistry.
• Catalyst Screening Libraries: A valuable component in high-throughput screening kits for identifying optimal catalyst systems for specific synthetic challenges.

Basic Information

Product Name	(1S,2S)-N,n-Bis[2-(Diphenylphosphino)Benzyl]Cyclohexane-1,2-Diamine, Min. 97%
CAS No.	174677-83-9
Molecular Formula	C46H48N2P2
Molecular Weight	690.84 g/mol
Synonyms	(1S,2S)-Cyclohexane-1,2-diamine, N,N-bis[2-(diphenylphosphino)benzyl]-; (S,S)-N,N-Bis[2-(Diphenylphosphino)benzyl]-1,2-cyclohexanediamine; (S,S)-CyDN; (S,S)-CyclohexaneDIAMINE-based Diphosphine Ligand; (1S,2S)-N,N-Bis[2-(Diphenylphosphino)benzyl]-1,2-cyclohexanediamine; (S,S)-N,N-Bis(o-(Diphenylphosphino)benzyl)-1,2-cyclohexanediamine; (S,S)-N,N-Bis(2-(Diphenylphosphanyl)benzyl)cyclohexane-1,2-diamine
EINECS	Contact for details

Quality Control

Our (1S,2S)-N,n-Bis[2-(Diphenylphosphino)Benzyl]Cyclohexane-1,2-Diamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and chiral assay, NMR for structural confirmation, and elemental analysis, to ensure it meets the specified minimum 97% purity and enantiomeric excess standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (argon or nitrogen) in a cool, dry place at a controlled room temperature (15-25°C). Minimize exposure to air and moisture during handling to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	Min. 97.0%
Chiral Purity (HPLC)	Min. 99.0% ee
Water Content (KF)	Max. 0.5%
Residue on Ignition	Max. 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.