Description

(S,S)-1,2-Bis{{[2-(Diphenylphosphino)Phenyl]Methylene}Amino}Cyclohexane is a high-purity, chiral bisphosphine ligand of significant importance in asymmetric synthesis. Its core value lies in its ability to induce high enantioselectivity in transition metal-catalyzed reactions, enabling the production of optically active intermediates. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control.

Application

• As a chiral ligand for asymmetric hydrogenation of olefins, ketones, and imines.
• Catalyst component in enantioselective C-C bond-forming reactions, such as cross-coupling and allylic substitution.
• Key reagent for the synthesis of chiral active pharmaceutical ingredients (APIs) and advanced intermediates.
• Use in the development of agrochemicals and flavors & fragrances requiring specific stereoisomers.
• Fundamental research tool in organometallic chemistry and catalyst design.
• Production of specialty polymers with controlled tacticity.

Basic Information

Product Name	(S,S)-1,2-Bis{{[2-(Diphenylphosphino)Phenyl]Methylene}Amino}Cyclohexane
CAS No.	174677-82-8
Molecular Formula	C46H42N2P2
Molecular Weight	684.80 g/mol
Synonyms	(S,S)-Cyclohexanediamine-N,N'-bis(2-diphenylphosphinobenzylidene); (S,S)-Jacobsen's Ligand; (S,S)-Bis[(2-diphenylphosphino)benzylidene]cyclohexane-1,2-diamine; (S,S)-DACH-Phenyl Trost Ligand; (S,S)-Trost Ligand; (1S,2S)-(-)-1,2-Diaminocyclohexane-N,N'-bis(2-diphenylphosphinobenzylidene); (S,S)-DPPBA; (S,S)-Bis(phosphino) diimine ligand
EINECS	Contact for details

Quality Control

Our (S,S)-1,2-Bis{{[2-(Diphenylphosphino)Phenyl]Methylene}Amino}Cyclohexane is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral purity. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label. This compound is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Keep container tightly sealed in a cool, dry, and well-ventilated place.

Specification

Item	Specification
Appearance	Yellow to orange powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.