Description

(R)-n-Boc-2-Phenylpyrrolidine is a high-purity chiral building block and intermediate of significant importance in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets and other therapeutic areas.
• Asymmetric Catalysis Ligand Precursor: Used in the development and synthesis of chiral ligands for transition metal-catalyzed reactions.
• Peptidomimetic & Proline Derivative Synthesis: Serves as a protected (R)-2-phenylpyrrolidine scaffold for constructing peptidomimetics and other bioactive molecules.
• Agrochemical Research: Employed in the discovery and development of chiral active ingredients for crop protection.
• Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry and for exploring new synthetic pathways.

Basic Information

Product Name	(R)-n-Boc-2-Phenylpyrrolidine
CAS No.	174311-02-5
Molecular Formula	C16H23NO2
Molecular Weight	261.36 g/mol
Synonyms	(R)-1-Boc-2-Phenylpyrrolidine; (R)-2-Phenyl-1-(tert-butoxycarbonyl)pyrrolidine; (R)-N-Boc-2-Phenylpyrrolidine; tert-Butyl (R)-2-phenylpyrrolidine-1-carboxylate; (R)-1-(tert-Butoxycarbonyl)-2-phenylpyrrolidine; (R)-N-(tert-Butoxycarbonyl)-2-phenylpyrrolidine; (R)-2-Phenyl-N-Boc-pyrrolidine
EINECS	Contact for details

Quality Control

Our (R)-n-Boc-2-Phenylpyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for research and production use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.