Description

1-(Methoxymethoxy)-4-(Trifluoromethyl)Benzene is a specialized aromatic ether building block of significant interest in advanced organic synthesis. Its molecular structure, featuring a protected hydroxyl equivalent and a robust trifluoromethyl group, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries, where it is used to introduce fluorinated motifs and functional handles into target molecules, thereby influencing bioavailability, metabolic stability, and binding affinity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic systems to enhance lipophilicity and metabolic resistance.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), contributing to charge transport and stability.
• Organic Synthesis & Catalysis Research: Employed in academic and industrial R&D for constructing complex organic frameworks, including ligands for catalysis and novel polymeric materials.
• Fluorine Chemistry Studies: Acts as a model compound for investigating the reactivity and incorporation of fluorinated aromatic groups in various chemical transformations.

Basic Information

Product Name	1-(Methoxymethoxy)-4-(Trifluoromethyl)Benzene
CAS No.	174265-24-8
Molecular Formula	C10H11F3O2
Molecular Weight	220.19 g/mol
Synonyms	4-(Trifluoromethyl)phenyl methoxymethyl ether; α-Methoxy-4-(trifluoromethyl)benzyl methyl ether; 1-Methoxymethoxy-4-(trifluoromethyl)benzene; p-(Trifluoromethyl)phenyl methoxymethyl ether; MOM ether of 4-(Trifluoromethyl)phenol; (4-(Trifluoromethyl)phenoxy)methoxymethane
EINECS	Contact for details

Quality Control

Our production of 1-(Methoxymethoxy)-4-(Trifluoromethyl)Benzene adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques including GC, HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.