Description

3α-Hydroxydesoxy Artemether is a key pharmaceutical intermediate and derivative of artemisinin, a sesquiterpene lactone. This compound is of significant commercial and research interest for the development of next-generation antimalarial agents and other therapeutic applications. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry. The product is supplied with a focus on high purity and consistency to meet stringent research and production requirements.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel artemisinin-based antimalarial drugs and their analogs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new therapeutic compounds with improved efficacy and reduced resistance.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Active Pharmaceutical Ingredient (API) Development: Investigated for use in the development and scale-up of new API candidates.
• Biochemical Research: Employed in studies exploring the mechanism of action of artemisinin derivatives against *Plasmodium* parasites and other pathogens.
• Process Chemistry: Used in optimizing synthetic routes and scaling up production processes for artemisinin derivatives.

Basic Information

Item	Detail
Product Name	3α-Hydroxydesoxy Artemether
CAS No.	174097-70-2
Molecular Formula	C16H26O5
Molecular Weight	298.37 g/mol
Synonyms	3α-Hydroxydeoxyartemether; 3α-Hydroxy-desoxy-artemether; 3α-Hydroxy-11-epi-artemether; Deoxyartemether 3α-ol; (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-ol, 3-ether with methyl alcohol; Arteether derivative
EINECS	Contact for details

Quality Control

Our 3α-Hydroxydesoxy Artemether is manufactured under controlled conditions to ensure high chemical purity and batch-to-batch consistency. Quality is verified through a comprehensive suite of analytical techniques including HPLC, GC, and NMR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for every batch, detailing purity, identity, and impurity profiles. Our quality system is designed to support cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.