Description

Interleukin-1 Receptor-Related Protein CAS NO 174068-24-7 is a high-purity recombinant protein that plays a critical role in modulating inflammatory and immune responses by acting as a decoy receptor for interleukin-1. This compound is essential for advanced biochemical research and therapeutic development, offering researchers a reliable tool for studying cytokine signaling pathways. It is primarily utilized by biotechnology firms, pharmaceutical R&D departments, and academic research institutions focused on immunology, autoimmune diseases, and novel biologic drug discovery.

Application

• Biochemical Research: Used as a key reagent in studying the IL-1 signaling pathway, receptor-ligand interactions, and inflammatory cascades.
• Drug Discovery & Development: Serves as a target or tool compound in high-throughput screening (HTS) assays for identifying novel anti-inflammatory therapeutics.
• Diagnostic Development: Employed in the development and calibration of immunoassays (e.g., ELISA) to detect and quantify interleukin-1 activity in biological samples.
• Cell Culture & In Vitro Studies: Applied in cell-based assays to investigate the effects of IL-1 blockade on various cell types, including immune cells.
• Protein Standard & Control: Acts as a purified standard for protein quantification, quality control, and method validation in analytical laboratories.
• Therapeutic Protein Research: Studied for its potential as a biologic agent or as a component in fusion proteins designed to modulate immune responses.

Basic Information

Product Name	Interleukin-1 Receptor-Related Protein
CAS No.	174068-24-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	IL-1 Receptor-Related Protein; IL-1 RRP; IL-1 Decoy Receptor; Interleukin-1 Receptor-like Protein; Soluble IL-1 Receptor Accessory Protein; IL-1 RAcP; IL1RAP; TIGIRR-2; C3orf13
EINECS	Contact for details

Quality Control

Our Interleukin-1 Receptor-Related Protein is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Quality is verified through a comprehensive suite of analytical techniques, including SDS-PAGE, HPLC, and mass spectrometry, to confirm purity, identity, and endotoxin levels. A Certificate of Analysis (COA) detailing specific test results is provided with each shipment to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted protein solutions should be aliquoted and stored at -80°C to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use in a low-humidity environment.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Purity (SDS-PAGE)	≥ 95%
Identification (Mass Spec)	Conforms
Endotoxin Level (LAL)	< 1.0 EU/μg
Biological Activity (Cell-based assay)	Contact for details
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.