Description

2-[4-(Trifluoromethyl)Phenyl]-1,3-Thiazole-4-Carbaldehyde is a high-value fluorinated heterocyclic building block, prized for its unique trifluoromethylphenyl and aldehyde functionalities. This compound is critical for introducing specific electronic and steric properties into target molecules, enabling the development of advanced materials and active ingredients. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry, crop protection, and functional material synthesis.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of novel drug candidates, particularly for kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) active compounds.
• Agrochemical Active Ingredient Precursor: Used in the development of next-generation herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, useful in asymmetric synthesis and polymerization processes.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and fluorescent dyes due to its electron-withdrawing characteristics and ability to form conjugated systems.
• Custom Synthesis and Contract Manufacturing: An essential building block for custom chemical synthesis (CRO/CMO) services catering to client-specific molecular design and scale-up projects.

Basic Information

Product Name	2-[4-(Trifluoromethyl)Phenyl]-1,3-Thiazole-4-Carbaldehyde
CAS No.	174006-70-3
Molecular Formula	C11H6F3NOS
Molecular Weight	257.23 g/mol
Synonyms	4-(Trifluoromethyl)phenyl-1,3-thiazole-4-carboxaldehyde; 4-Formyl-2-[4-(trifluoromethyl)phenyl]thiazole; 2-(4-Trifluoromethylphenyl)thiazole-4-carbaldehyde; 2-(alpha,alpha,α-Trifluoro-p-tolyl)-4-thiazolecarboxaldehyde; 174006-70-3; 4-Thiazolecarboxaldehyde, 2-[4-(trifluoromethyl)phenyl]-; p-(Trifluoromethyl)phenyl thiazole carbaldehyde
EINECS	Contact for details

Quality Control

Our production of 2-[4-(Trifluoromethyl)Phenyl]-1,3-Thiazole-4-Carbaldehyde adheres to stringent in-process controls and final batch analysis to ensure consistent high purity and chemical identity. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, impurity profiles, and physical characteristics. Our quality system is designed to support cGMP and ISO standards for traceability and reliability, making it suitable for demanding R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent oxidation. Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.