Description

4,6-Difluoro-2,3-Dihydro-1H-Inden-1-Ol CAS NO 173998-55-5 is a high-purity fluorinated indanol derivative, a crucial chiral building block in modern synthetic chemistry. Its value lies in its unique molecular scaffold, which is essential for constructing complex molecules with specific stereochemistry and bioactivity. This compound is primarily needed by pharmaceutical R&D and fine chemical synthesis teams for developing advanced active pharmaceutical ingredients (APIs) and agrochemical intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and pesticides, where the difluoro and indanol motifs contribute to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of fluorinated organic compounds for electronic materials and specialty polymers.
• Academic & Industrial R&D: A valuable tool compound for methodological studies in organic synthesis, including fluorination and stereoselective reactions.

Basic Information

Item	Details
Product Name	4,6-Difluoro-2,3-Dihydro-1H-Inden-1-Ol
CAS No.	173998-55-5
Molecular Formula	C9H8F2O
Molecular Weight	170.16 g/mol
Synonyms	4,6-Difluoro-1-indanol; 4,6-Difluoro-2,3-dihydro-1H-inden-1-ol; 1H-Inden-1-ol, 4,6-difluoro-2,3-dihydro-; 4,6-Difluoroindan-1-ol; (RS)-4,6-Difluoro-2,3-dihydro-1H-inden-1-ol; (±)-4,6-Difluoro-1-indanol
EINECS	Contact for details

Quality Control

Our 4,6-Difluoro-2,3-Dihydro-1H-Inden-1-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.