Description

5,6-Difluoro-2,3-Dihydro-1H-Inden-1-Ol is a high-purity fluorinated indanol derivative, serving as a critical chiral building block and synthetic intermediate in advanced organic synthesis. Its unique bicyclic structure and fluorine substitution pattern make it a valuable scaffold for developing novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: Key chiral precursor for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Building block for developing advanced fluorinated pesticides and herbicides, leveraging fluorine's ability to enhance bioavailability and metabolic stability.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis and organometallic complexes.
• Material Science Research: Intermediate for synthesizing fluorinated organic semiconductors and liquid crystal materials.
• Chemical Biology Probes: Scaffold for creating fluorinated molecular probes to study enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke organic synthesis projects requiring high-purity, complex fluorinated intermediates.

Basic Information

Product Name	5,6-Difluoro-2,3-Dihydro-1H-Inden-1-Ol
CAS No.	173996-14-0
Molecular Formula	C9H8F2O
Molecular Weight	170.16 g/mol
Synonyms	5,6-Difluoro-1-indanol; 5,6-Difluoro-2,3-dihydro-1H-inden-1-ol; 1H-Inden-1-ol, 5,6-difluoro-2,3-dihydro-; 5,6-Difluoroindan-1-ol; (±)-5,6-Difluoro-2,3-dihydro-1H-inden-1-ol; rac-5,6-Difluoro-2,3-dihydro-1H-inden-1-ol
EINECS	Contact for details

Quality Control

Our 5,6-Difluoro-2,3-Dihydro-1H-Inden-1-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and MS, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.