Description

Fmoc-Cys(3-(Boc-Amino)-Propyl)-Oh is a specialized, orthogonally protected cysteine derivative designed for advanced solid-phase peptide synthesis (SPPS). This compound is critical for introducing cysteine residues with a selectively removable side-chain protecting group, enabling the precise construction of complex peptides and proteins. It is an essential building block for researchers and manufacturers in pharmaceutical development, biotechnology, and chemical biology who require high-purity intermediates for synthesizing therapeutic peptides, protein mimics, and bioconjugates.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the automated synthesis of peptides containing cysteine.
• Pharmaceutical Intermediates: Used in the research and production of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Disulfide Bridge Formation: Enables the controlled formation of intramolecular and intermolecular disulfide bonds, which are crucial for the tertiary structure and biological activity of many peptides.
• Bioconjugation and Labeling: The free thiol group, after deprotection, serves as a reactive handle for site-specific conjugation with fluorophores, polymers, or other biomolecules.
• Chemical Biology Probes: Synthesis of modified peptides used as tools for studying protein-protein interactions and enzyme activity.
• Material Science: Building block for creating peptide-based polymers and hydrogels with specific cross-linking properties.

Basic Information

Product Name	Fmoc-Cys(3-(Boc-Amino)-Propyl)-Oh
CAS No.	173963-91-2
Molecular Formula	C27H34N2O6S
Molecular Weight	514.64 g/mol
Synonyms	Fmoc-Cys(3-(Boc-NH)-propyl)-OH; N-α-Fmoc-S-[3-[(tert-Butoxycarbonyl)amino]propyl]-L-cysteine; Fmoc-Cys(Acp(Boc))-OH; Fmoc-L-Cys(3-(Boc-amino)propyl)-OH; Fmoc-Cys(3-(N-Boc-amino)propyl)-OH; N-(9-Fluorenylmethoxycarbonyl)-S-[3-[(tert-butoxycarbonyl)amino]propyl]-L-cysteine; (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[3-[(2-methylpropan-2-yl)oxycarbonylamino]propyl]sulfanylpropanoic acid
EINECS	Contact for details

Quality Control

Our Fmoc-Cys(3-(Boc-Amino)-Propyl)-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and traceability for your research and cGMP manufacturing needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.