Description

Tizoxanide is a synthetic nitrothiazole derivative with significant antiprotozoal and broad-spectrum antimicrobial activity. This compound is a key intermediate in the synthesis of the important antiparasitic drug Nitazoxanide, which is widely used in human and veterinary medicine. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of antiparasitic therapeutics.

Application

• Pharmaceutical Active Ingredient (API) Synthesis: As the primary active metabolite and synthetic precursor for the production of Nitazoxanide.
• Antiparasitic Drug Development: For research and formulation of new therapeutic agents targeting protozoan infections like giardiasis and cryptosporidiosis.
• Veterinary Medicine: Used in the development of treatments for parasitic infections in livestock and companion animals.
• Biochemical Research: As a reference standard or tool compound in pharmacological studies investigating anaerobic metabolism and antiparasitic mechanisms of action.
• Intermediate for Analogues: Serves as a core structure for the chemical synthesis of novel nitrothiazole analogues with potential enhanced efficacy.

Basic Information

Product Name	Tizoxanide
CAS No.	173903-47-4
Molecular Formula	C12H7N3O5S
Molecular Weight	305.26 g/mol
Synonyms	2-Hydroxy-N-(5-nitro-2-thiazolyl)benzamide; Desacetyl-nitazoxanide; TIZ; 2-Benzamido-5-nitrothiazole; [2-[(5-Nitro-1,3-thiazol-2-yl)carbamoyl]phenyl] acetate (hydrolyzed form); NTZ metabolite; Nitazoxanide impurity B; Nitazoxanide related compound A
EINECS	Contact for details

Quality Control

Our Tizoxanide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identification by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets high-grade pharmaceutical standards. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to pale yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.