Description

3-Chloro-5-Methyl-4-Hydroxybenzonitrile is a versatile halogenated aromatic nitrile derivative that serves as a key synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring chloro, methyl, and hydroxy substituents, makes it a valuable building block for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for molecules targeting specific biological pathways.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators, leveraging its halogenated aromatic core.
• Liquid Crystal & OLED Material Research: Serves as a building block for creating specialized organic molecules used in electronic displays and optoelectronic devices.
• Polymer & Resin Modification: Employed to introduce functional groups into polymer chains, enhancing material properties like thermal stability or chemical resistance.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing complex dyes and organic pigments, contributing to colorant development.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Heck) for constructing biaryl systems important in medicinal chemistry.

Basic Information

Product Name	3-Chloro-5-Methyl-4-Hydroxybenzonitrile
CAS No.	173900-45-3
Molecular Formula	C8H6ClNO
Molecular Weight	167.59 g/mol
Synonyms	4-Hydroxy-3-chloro-5-methylbenzonitrile; 3-Chloro-5-methyl-4-hydroxybenzonitrile; 4-Cyano-2-chloro-6-methylphenol; 2-Chloro-6-methyl-4-cyanophenol; Benzonitrile, 3-chloro-5-methyl-4-hydroxy-; 173900-45-3; 4-Hydroxy-3-chloro-5-methyl-benzonitrile
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-5-Methyl-4-Hydroxybenzonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet the exacting standards required for synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, and we support compliance with relevant regulatory frameworks for our customers' target markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.