Description

(S)-tert-Butyl (4-Methyl-1-Morpholino-1-Oxopentan-2-Yl)Carbamate is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and metabolic disorders. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers engaged in the production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of potent protease inhibitors and other bioactive molecules.
• Peptidomimetic Research: Serves as a protected amino acid derivative for constructing peptide analogs with enhanced stability and bioavailability.
• Drug Discovery & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization campaigns.
• Asymmetric Synthesis: Employed as a starting material or intermediate in catalytic asymmetric reactions to introduce stereochemical complexity.
• Custom Synthesis: A foundational component for contract research and manufacturing organizations (CROs/CMOs) producing custom APIs for clinical trials.

Basic Information

Product Name	(S)-tert-Butyl (4-Methyl-1-Morpholino-1-Oxopentan-2-Yl)Carbamate
CAS No.	173899-64-4
Molecular Formula	C15H28N2O4
Molecular Weight	300.40 g/mol
Synonyms	(S)-tert-Butyl (4-methyl-1-morpholino-1-oxopentan-2-yl)carbamate; (S)-2-((tert-Butoxycarbonyl)amino)-4-methyl-1-morpholinopentan-1-one; Boc-L-Leu-Morpholide; Boc-Leu-Morpholine; tert-Butyl (S)-(4-methyl-1-morpholino-1-oxopentan-2-yl)carbamate; (S)-Boc-Leu-Morpholine; N-Boc-L-leucine morpholide; (S)-N-Boc-Leucine Morpholide
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl (4-Methyl-1-Morpholino-1-Oxopentan-2-Yl)Carbamate is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.