Description

5-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}(Methyl)Amino)Pentanoic Acid is a specialized Fmoc-protected amino acid derivative, a critical building block in modern solid-phase peptide synthesis (SPPS). Its value lies in providing a protected, reactive handle that enables the controlled, sequential assembly of complex peptides and peptidomimetics. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors developing therapeutic peptides, diagnostic agents, and advanced biomaterials.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid derivative for the automated, stepwise construction of custom peptide sequences.
• Pharmaceutical R&D: Synthesis of novel peptide-based drug candidates, including hormone analogs, antimicrobial peptides, and targeted therapeutics.
• Peptidomimetic Design: Incorporation of non-natural amino acid structures to enhance the metabolic stability and bioavailability of peptide leads.
• Bioconjugation: Used to introduce specific functional groups or linker arms onto peptides for coupling with other molecules, such as dyes, polymers, or drug payloads.
• Combinatorial Chemistry: A valuable reagent in libraries for high-throughput screening to discover new bioactive compounds.
• Academic Research: Fundamental studies in biochemistry, molecular biology, and chemical biology exploring protein-protein interactions and signaling pathways.

Basic Information

Product Name	5-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}(Methyl)Amino)Pentanoic Acid
CAS No.	173690-48-7
Molecular Formula	C21H23NO4
Molecular Weight	353.41 g/mol
Synonyms	Fmoc-N-methyl-5-aminopentanoic acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-5-aminopentanoic acid; Nα-Fmoc-Nα-methyl-ornithine; 5-[(Fmoc)(methyl)amino]pentanoic acid; Fmoc-N-Me-Orn-OH; N-Fmoc-N-methyl-1,5-diaminopentanoic acid; Nα-Fmoc-Nα-methyl-L-ornithine (common for the L-isomer); N-Methyl-N-Fmoc-5-aminovaleric acid
EINECS	Contact for details

Quality Control

Our production of this high-purity peptide synthesis reagent adheres to stringent quality protocols. Every batch is characterized and tested to ensure exceptional purity and consistency, meeting the exacting standards required for sensitive synthetic applications. Comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry, is documented. Certificates of Analysis (COA) are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.