Description

6-((((9H-Fluoren-9-Yl)Methoxy)Carbonyl)(Methyl)Amino)Hexanoic Acid is a specialized Fmoc-protected amino acid derivative, serving as a crucial building block in solid-phase peptide synthesis (SPPS). Its primary value lies in enabling the controlled introduction of a methylated amino group with a flexible hexanoic acid linker, which is essential for creating modified peptides with enhanced stability, bioavailability, or specific functional properties. This high-purity intermediate is critically needed by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in the production of therapeutic peptides, diagnostic probes, and advanced biomaterials.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid derivative for the sequential assembly of custom peptide sequences.
• Pharmaceutical Intermediates: In the research and development of novel peptide-based therapeutics, including hormone analogs and enzyme inhibitors.
• Bioconjugation and Linker Chemistry: The hexanoic acid spacer facilitates the attachment of peptides to other molecules, surfaces, or carriers for drug delivery systems and diagnostic assays.
• Chemical Biology Probes: For synthesizing labeled or modified peptides used to study protein-protein interactions and cellular processes.
• Material Science: Incorporation into peptide-based polymers and hydrogels for biomedical and nanotechnology applications.
• Academic and Industrial R&D: A fundamental reagent for synthetic chemistry laboratories exploring new peptide architectures and functions.

Basic Information

Product Name	6-((((9H-Fluoren-9-Yl)Methoxy)Carbonyl)(Methyl)Amino)Hexanoic Acid
CAS No.	173690-47-6
Molecular Formula	C25H29NO4
Molecular Weight	407.50 g/mol
Synonyms	Fmoc-N-Me-6-Ahx-OH; N-α-Fmoc-N-ε-methyl-L-lysine; Fmoc-N-methyl-6-aminohexanoic acid; 6-[(9H-Fluoren-9-ylmethoxy)carbonyl(methyl)amino]hexanoic acid; Nε-Methyl-Nα-Fmoc-L-lysine; Fmoc-Nε-Me-Lys-OH; N-Methyl-N-((9H-fluoren-9-ylmethoxy)carbonyl)-6-aminohexanoic acid; Fmoc-Lys(Me)-OH
EINECS	Contact for details

Quality Control

Our 6-((((9H-Fluoren-9-Yl)Methoxy)Carbonyl)(Methyl)Amino)Hexanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and NMR for structural confirmation, to ensure it meets the high standards required for peptide synthesis and pharmaceutical research. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.